Article
Acute functional tolerance to ethanol and fear conditioning are genetically correlated in mice.
Alcoholism, clinical and experimental research - 1 Nov 1998
Radcliffe R A, Erwin V G, Wehner J M
Abstract excerpt
It has been speculated that tolerance to alcohol involves some form of neuronal plasticity that is similar to or the same as that mediating learning and memory. To investigate this possibility further, we tested the hypothesis that acute functional tolerance (AFT) to alcohol is genetically correlated to a Pavlovian learning task: fear conditioning. Mice selectively bred for differences in ability to acquire AFT...
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