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Article

Accurate stabilities of laccase mutants predicted with a modified FoldX protocol.

Journal of chemical information and modeling - 26 Nov 2012

Christensen Niels J, Kepp Kasper P

Abstract excerpt

Fungal laccases are multicopper enzymes of industrial importance due to their high stability, multifunctionality, and oxidizing power. This paper reports computational protocols that quantify the relative stability (ΔΔG of folding) of mutants of high-redox-potential laccases (TvLIIIb and PM1L) with up to 11 simultaneously mutated sites with good correlation against experimental stability trends. Molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23102044
DOI: 10.1021/ci300398z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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