Article
Polymorphisms in the p63 and p73 genes are associated with ovarian cancer risk and clinicopathological variables.
Journal of experimental & clinical cancer research : CR - 24 Oct 2012
Guan Xiao, Zhang Ning, Yin Yongshuo, Kong Beihua, Yang Qifeng, Han Zhiyan, Yang Xingsheng
Abstract excerpt
OBJECTIVE: p73 and p63 are two structural and functional homologs of p53, and their biological functions in cancer progression have attracted attention due to the presence of variants generated by genetic polymorphisms. Recently, three single nucleotide polymorphisms (SNPs) in the p63 and p73 genes have been associated with female reproduction. In the present study, we aimed to evaluate the relationship between...
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