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Article

The TP73 gene polymorphism (rs4648551, A>G) is associated with diminished ovarian reserve.

PloS one - 1 Jan 2015

Vagnini Laura Diniz, Renzi Adriana, Oliveira-Pelegrin Gabriela Ravanelli, Canas Maria do Carmo Tomitão, Petersen Claudia Guilhermino, Mauri Ana Lucia, Oliveira João Batista Alcantara, Baruffi Ricardo Luiz Razera, Cavagna Mario, Franco Junior José Gonçalves

Abstract excerpt

It's known that the members of the TP53 family are involved in the regulation of female reproduction. Studies in mice showed that the TP73 gene (member of this family) plays a role in the size of follicular pool, ovulation rate and maintenance of genomic stability. In the present study we analyzed data from 605 patients with ≤ 37 years attending their first intracytoplasmic sperm injection (ICSI). The association...

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Identifiers

PMID: 25794170
DOI: 10.1371/journal.pone.0120048
PMCID: PMC4368621

Genes

AMH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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