Article
A genetic variant in p63 (rs17506395) is associated with breast cancer susceptibility and prognosis.
Gene - 10 Feb 2014
Zhang Ning, Huo Qiang, Wang Xiaolong, Chen Xi, Long Li, Guan Xiao, Jiang Liyu, Ma Tingting, Hu Wenwei, Yang Qifeng
Abstract excerpt
BACKGROUND: p63, homologous to p53, has been investigated to be involved in various aspects of tumorigenesis and cancer progression. Recently, we have identified a functional single nucleotide polymorphism (SNP) rs17506395 (T>G) in p63 which was associated with female reproduction and ovarian cancer development. The present study aimed to evaluate the association of rs17506395 genotypes with breast cancer...
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