Article
The induction of dominant lethal mutations upon chronic administration of khat (Catha edulis) in albino mice.
Toxicology letters - 1 Feb 1990
Tariq M, Qureshi S, Ageel A M, al-Meshal I A
Abstract excerpt
The mutagenicity of a methanolic extract of khat has been evaluated on male germ cells using the dominant lethal test in albino mice. An aqueous solution of khat extract was administered orally in doses of 50, 100 and 200 mg/kg body wt., respectively, to 3 different groups of male mice for a peri...
Topics
- Animals
- Catha
- Genes, Dominant
- Genes, Lethal
- Male
- Mice
- Mutation
- Plant Extracts
- Substance-Related Disorders