Assessment of mutagenic potential of thiram.

doi:10.1016/s0278-6915(97)00017-3

Article

Assessment of mutagenic potential of thiram.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 May 1997

Agrawal R C, Shukla Y, Mehrotra N K

Abstract excerpt

Thiram is a widely used dithiocarbamate fungicide. In this study, the mutagenicity of thiram was investigated using the micronucleus and dominant lethal tests in Swiss albino mice. A single ip injection of 100 mg thiram/kg body weight, which is the maximum tolerated dose (MTD), significantly indu...

Topics

Animals
Bone Marrow
Embryonic Development
Female
Fungicides, Industrial
Male
Mice
Micronucleus Tests
Mutation
Pregnancy
Spermatogenesis
Thiram

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