Article
Assessment of mutagenic potential of thiram.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 May 1997
Agrawal R C, Shukla Y, Mehrotra N K
Abstract excerpt
Thiram is a widely used dithiocarbamate fungicide. In this study, the mutagenicity of thiram was investigated using the micronucleus and dominant lethal tests in Swiss albino mice. A single ip injection of 100 mg thiram/kg body weight, which is the maximum tolerated dose (MTD), significantly induced micronucleus formation in bone marrow cells after 30 and 48 hr of exposure; 50% and 25% of the MTD also induced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.