Article
RAD51 gene polymorphisms and sporadic colorectal cancer risk in Poland.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Nov 2012
Romanowicz-Makowska Hanna, Samulak Dariusz, Michalska Magdalena, Sporny Stanisław, Langner Ewa, Dziki Adam, Sychowski Radosław, Smolarz Beata
Abstract excerpt
BACKGROUND: DNA repair processes play an important role in protection against carcinogenic factors. Mutations in DNA repair genes, which code proteins engaged in repair processes, may lead to carcinogenesis and among others also to colorectal cancer (CRC) development. The genetic variability in RAD51 may contribute to the appearance and progression of various cancers including CRC. The aim of the study was to...
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