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Article

The genetic polymorphisms of HLA are strongly correlated with the disease severity after Hantaan virus infection in the Chinese Han population.

Clinical & developmental immunology - 1 Jan 2012

Ma Ying, Yuan Bin, Yi Jing, Zhuang Ran, Wang Jiuping, Zhang Yun, Xu Zhuwei, Zhang Yusi, Liu Bei, Wei Chao, Zhang Chunmei, Yang Angang, Jin Boquan

Abstract excerpt

The polymorphism of human leukocyte antigen (HLA), which is a genetic factor that influences the progression of hemorrhagic fever with renal syndrome (HFRS) after Hantaan virus (HTNV) infection, was incompletely understood. In this case-control study, 76 HFRS patients and 370 healthy controls of the Chinese Han population were typed for the HLA-A, -B, and -DRB1 loci. The general variation at the HLA-DRB1 locus...

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Identifiers

PMID: 23091554
DOI: 10.1155/2012/308237
PMCID: PMC3472611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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