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Article

Tumor necrosis factor-alpha genetic predisposing factors can influence clinical severity in nephropathia epidemica.

Viral immunology - 1 Jan 2006

Maes Piet, Clement Jan, Groeneveld Paul H P, Colson Paul, Huizinga Tom W J, Van Ranst Marc

Abstract excerpt

Severe human infection with Hantavirus is characterized by high fever, cold chills, thrombocytopenia, arterial hypotension, acute renal failure, and/or adult respiratory distress syndrome (ARDS)-like pulmonary involvement, but the clinical course varies greatly between individuals. We investigated whether genetically determined differences in tumor necrosis factor (TNF)-alpha production can influence the severity...

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Source

Identifiers

PMID: 16987073
DOI: 10.1089/vim.2006.19.558

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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