Article
Role of peripheral blood mononuclear cell (PBMC) phenotype changes in the pathogenesis of haemorrhagic fever with renal syndrome (HFRS).
Clinical and experimental immunology - 1 Feb 1999
Markotić A, Dasić G, Gagro A, Sabioncello A, Rabatić S, Kuzman I, Zgorelec R, Smoljan I, Beus I, Zupanc T A, Dekaris D
Abstract excerpt
Hantaviruses cause an important human illness, HFRS. Blood samples from 22 HFRS-positive, six seronegative patients and 15 healthy controls were examined in 1995, during the largest HFRS epidemic in Croatia. Results of double- and triple-colour immunofluorescence analysis showed an increased percentage of cytotoxic T cells (CD3+CD8+) in seropositive patients compared with seronegatives and healthy controls. The...
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