Article
Structural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB' mutant.
Antonie van Leeuwenhoek - 1 Aug 2008
Mishra Arun K, Klein Christina, Gurcha Sudagar S, Alderwick Luke J, Babu Ponnusamy, Hitchen Paul G, Morris Howard R, Dell Anne, Besra Gurdyal S, Eggeling Lothar
Abstract excerpt
The genus Corynebacterium is part of the phylogenetic group nocardioform actinomycetes, which also includes the genus Mycobacterium. Members of this phylogenetic group have a characteristic cell envelope structure, which is dominated by complex lipids and amongst these, lipoglycans are of particular interest. The disruption of NCgl2106 in C. glutamicum resulted in a mutant devoid of monoacylated...
Topics
- Biosynthetic Pathways
- Cell Line
- Corynebacterium glutamicum
- Humans
- Lipids
- Lipopolysaccharides
- Macrophages
- Mass Spectrometry
- Mutation
- Phosphatidylinositols