Article
The ABO blood group is a trans-species polymorphism in primates.
Proceedings of the National Academy of Sciences of the United States of America - 6 Nov 2012
Ségurel Laure, Thompson Emma E, Flutre Timothée, Lovstad Jessica, Venkat Aarti, Margulis Susan W, Moyse Jill, Ross Steve, Gamble Kathryn, Sella Guy, Ober Carole, Przeworski Molly
Abstract excerpt
The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes responsible for A and B specificity in all species sequenced to date. Whether this recurrence of A and B antigens is the result of an ancient polymorphism maintained...
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