Article
An integrative evolution theory of histo-blood group ABO and related genes.
Scientific reports - 13 Oct 2014
Yamamoto Fumiichiro, Cid Emili, Yamamoto Miyako, Saitou Naruya, Bertranpetit Jaume, Blancher Antoine
Abstract excerpt
The ABO system is one of the most important blood group systems in transfusion/transplantation medicine. However, the evolutionary significance of the ABO gene and its polymorphism remained unknown. We took an integrative approach to gain insights into the significance of the evolutionary process of ABO genes, including those related not only phylogenetically but also functionally. We experimentally created a...
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