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Article

Evolutionary dynamics of the human ABO gene.

Human genetics - 1 Sept 2008

Calafell Francesc, Roubinet Francis, Ramírez-Soriano Anna, Saitou Naruya, Bertranpetit Jaume, Blancher Antoine

Abstract excerpt

The ABO polymorphism has long been suspected to be under balancing selection. To explore this possibility, we analyzed two datasets: (1) a set of 94 23-Kb sequences in European- and African-Americans produced by the Seattle SNPs project, and (2) a set of 814 2-Kb sequences in O alleles from seven worldwide populations. A phylogenetic analysis of the Seattle sequences showed a complex pattern in which the action...

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Source

Identifiers

PMID: 18629539
DOI: 10.1007/s00439-008-0530-8

Genes

ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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