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Article

Cxcr4 regulation of interneuron migration is disrupted in 22q11.2 deletion syndrome.

Proceedings of the National Academy of Sciences of the United States of America - 6 Nov 2012

Meechan Daniel W, Tucker Eric S, Maynard Thomas M, LaMantia Anthony-Samuel

Abstract excerpt

Interneurons are thought to be a primary pathogenic target for several behavioral disorders that arise during development, including schizophrenia and autism. It is not known, however, whether genetic lesions associated with these diseases disrupt established molecular mechanisms of interneuron development. We found that diminished 22q11.2 gene dosage-the primary genetic lesion in 22q11.2 deletion syndrome...

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Identifiers

PMID: 23091025
DOI: 10.1073/pnas.1211507109
PMCID: PMC3494945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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