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Article

Identification of Burkholderia cenocepacia strain H111 virulence factors using nonmammalian infection hosts.

Infection and immunity - 1 Jan 2013

Schwager Stephan, Agnoli Kirsty, Köthe Manuela, Feldmann Friederike, Givskov Michael, Carlier Aurelien, Eberl Leo

Abstract excerpt

Burkholderia cenocepacia H111, a strain isolated from a cystic fibrosis patient, has been shown to effectively kill the nematode Caenorhabditis elegans. We used the C. elegans model of infection to screen a mini-Tn5 mutant library of B. cenocepacia H111 for attenuated virulence. Of the approximately 5,500 B. cenocepacia H111 random mini-Tn5 insertion mutants that were screened, 22 showed attenuated virulence in...

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Identifiers

PMID: 23090963
DOI: 10.1128/IAI.00768-12
PMCID: PMC3536147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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