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A Functional Phenylacetic Acid Catabolic Pathway Is Required for Full Pathogenicity of <i>Burkholderia cenocepacia</i> in the <i>Caenorhabditis elegans</i> Host Model

6 Sept 2008

Abstract excerpt

Burkholderia cenocepacia is a member of the Burkholderia cepacia complex, a group of metabolically versatile bacteria that have emerged as opportunistic pathogens in cystic fibrosis and immunocompromised patients. Previously a screen of transposon mutants in a rat pulmonary infection model identified an attenuated mutant with an insertion in paaE, a gene related to the phenylacetic acid (PA) catabolic pathway. In...

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PMID: 18776009
DOI: 10.1128/jb.00481-08

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