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Article

A Unique Regulator Contributes to Quorum Sensing and Virulence in Burkholderia cenocepacia

18 May 2012

Abstract excerpt

Burkholderia cenocepacia causes chronic and life-threatening respiratory infections in immunocompromized people. The B. cenocepacia N-acyl-homoserine lactone (AHL)-dependent quorum sensing system relies on the production of AHLs by the synthases CepI and CciI while CepR, CciR and CepR2 control expression of many genes important for pathogenesis. Downstream from, and co-transcribed with cepI, lies BCAM1871...

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PMID: 22624054
DOI: 10.1371/journal.pone.0037611

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