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Article

Thr136Ile polymorphism of human vesicular monoamine transporter-1 (SLC18A1 gene) influences its transport activity in vitro.

Neuro endocrinology letters - 1 Jan 2012

Khalifa Ahmed M, Watson-Siriboe Abena, Shukry Sally G, Chiu Wan-Ling, Nelson Margaret E, Geng Yingying, Fischer-Stenger Krista, Porter Joseph H, Stewart Jennifer K

Abstract excerpt

OBJECTIVES: Although single nucleotide polymorphisms of the human vesicular monoamine transporter 1 (hVMAT1) gene SLC18A1 have been associated with neuropsychiatric disorders, there is limited information on the function of naturally occurring hVMAT1 variant proteins. This study evaluated transport activity of full length hVMAT1 isoform-a (NP_003044.1) with a threonine (Thr) or isoleucine (Ile) at amino acid 136...

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PMID: 23090274

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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