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Article

Treatment of erectile dysfunction due to C677T mutation of the MTHFR gene with vitamin B6 and folic acid in patients non responders to PDE5i.

The journal of sexual medicine - 1 Jan 2010

Lombardo Francesco, Tsamatropoulos Petros, Piroli Emanuela, Culasso Franco, Jannini Emmanuele Angelo, Dondero Franco, Lenzi Andrea, Gandini Loredana

Abstract excerpt

INTRODUCTION: Epidemiological studies conducted on erectile dysfunction (ED) have demonstrated its close correlation with cardiovascular disease. Since hyperhomocysteinemia is considered an important cardiovascular risk factor, it could also be involved in the pathogenesis of ED. AIM: To study the role of the C677T MTHFR mutation with subsequent hyperhomocysteinemia in the determination of ED. METHODS: We studied...

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Source

Identifiers

PMID: 19694922
DOI: 10.1111/j.1743-6109.2009.01463.x

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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