Article
The genetics of ankylosing spondylitis and axial spondyloarthritis.
Rheumatic diseases clinics of North America - 1 Aug 2012
Robinson Philip C, Brown Matthew A
Abstract excerpt
Ankylosing spondylitis (AS) and spondyloarthritis are strongly genetically determined. The long-standing association with HLA-B27 is well described, although the mechanism by which that association induces AS remains uncertain. Recent developments include the description of HLA-B27 tag single nucleotide polymorphisms in European and Asian populations. An increasing number of non-MHC genetic associations have been...
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