Article
Role of mitochondrial DNA variants and copy number in diabetic atherogenesis.
Genetics and molecular research : GMR - 17 Sept 2012
Chien M C, Huang W T, Wang P W, Liou C W, Lin T K, Hsieh C J, Weng S W
Abstract excerpt
Hyperglycemia-induced reactive oxygen species production can cause diabetes and its complications, including atherosclerosis. The role of mitochondrial DNA variants and mitochondrial copy number in the pathogenesis of diabetic atherogenesis is not well understood. We examined 36 diabetic patients who had undergone amputation for diabetic foot and seven non-diabetic patients who had undergone amputation after...
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