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Article

GSTO2*N142D gene polymorphism associated with hypothyroidism in Italian patients.

Molecular biology reports - 1 Feb 2013

Piacentini Sara, Monaci Paola Maria, Polimanti Renato, Manfellotto Dario, Fuciarelli Maria

Abstract excerpt

Hypothyroidism is a multifactorial endocrinal disease characterized by abnormally low thyroid hormone production. Thyroiditis is one of the primary causes of hypothyroidism, as it is an increasing level of inflammation in the thyroid gland that could be due to a failure of the anti-inflammatory response. Glutathione S-transferases are biomarkers of inflammation and oxidative stress. These phase II enzymes play a...

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Source

Identifiers

PMID: 23079717
DOI: 10.1007/s11033-012-2253-0

Genes

GSTO2
GSTA1
GSTM1
GSTP1
GSTT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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