Potential link between MHC-self-peptide presentation and hematopoiesis; the analysis of HLA-DR expression in CD34-positive cells and self-peptide presentation repertoires of MHC molecules associated with paroxysmal nocturnal hemoglobinuria.

doi:10.1007/s12013-012-9435-1

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Article

Potential link between MHC-self-peptide presentation and hematopoiesis; the analysis of HLA-DR expression in CD34-positive cells and self-peptide presentation repertoires of MHC molecules associated with paroxysmal nocturnal hemoglobinuria.

Cell biochemistry and biophysics - 1 Apr 2013

Nowak Jacek, Wozniak Jolanta, Mendek-Czajkowska Ewa, Dlugokecka Agnieszka, Mika-Witkowska Renata, Rogatko-Koros Marta, Graczyk-Pol Elzbieta, Marosz-Rudnicka Anna, Dziopa Joanna, Golec Agnieszka, Kopec-Szlezak Joanna, Warzocha Krzysztof

Abstract excerpt

The mechanisms of MHC allele associations with paroxysmal nocturnal hemoglobinuria (PNH) and its aplastic anemia subtype (AA/PNH) remain unclear. It might be dependent on MHC molecule functional properties, such as a scope and frequency of antigen sampling and presentation. For documented PNH-associated MHC alleles we analyzed current reference databases on MHC molecule-eluted peptide presentation repertoires and...

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Identifiers

PMID: 23076633
DOI: 10.1007/s12013-012-9435-1
PMCID: PMC3601265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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