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Article

The patterns of MHC association in aplastic and non-aplastic paroxysmal nocturnal hemoglobinuria.

Archivum immunologiae et therapiae experimentalis - 1 Jun 2011

Nowak Jacek, Mika-Witkowska Renata, Mendek-Czajkowska Ewa, Rogatko-Koroś Marta, Graczyk-Pol Elżbieta, Pyl Hanna, Klimczak Aneta, Wójcik Małgorzata, Prochorec-Sobieszek Monika, Maryniak Renata, Zupańska Barbara

Abstract excerpt

The deficiency of glycosyl-phosphatidylinositol (GPI)-anchored proteins in plasma membranes of PIG-A gene mutated hematopoietic stem cells (HSCs) is so far insufficient to explain the domination of paroxysmal nocturnal hemoglobinuria (PNH) clone over the normal HSC. We attempted to elucidate possible link between MHC and initial severe aplastic anemia (ISAA/PNH) type and non-aplastic (n/PNH) outcome of PNH. In 50...

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PMID: 21442308
DOI: 10.1007/s00005-011-0125-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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