Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A systematic analysis of bone marrow cells by flow cytometry defines a specific phenotypic profile beyond GPI deficiency in paroxysmal nocturnal hemoglobinuria.

Cytometry. Part B, Clinical cytometry - 1 Mar 2013

Mannelli Francesco, Bencini Sara, Peruzzi Benedetta, Cutini Ilaria, Sanna Alessandro, Benelli Matteo, Magi Alberto, Gianfaldoni Giacomo, Rotunno Giada, Carrai Valentina, Gelli Anna Maria Grazia, Valle Veronica, Santini Valeria, Notaro Rosario, Luzzatto Lucio, Bosi Alberto

Abstract excerpt

BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is a unique disorder caused by a PIG-A gene mutation in a stem cell clone. Its clinical picture can sometimes make challenging the distinction from other disorders, and especially from myelodysplastic syndromes (MDS), since both diseases correlate with cytopenias and morphological abnormalities of bone marrow (BM) cells. Recently, flow cytometry (FC) has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD36 Antigens
Share to CD55 Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD59 Antigens

Share to Glycosylphosphatidylinositols

Share to Hemoglobinuria, Paroxysmal

Share to Karyotype

Share to Leukocyte Common Antigens

Share to Neprilysin

Source

Identifiers

PMID: 23281097
DOI: 10.1002/cyto.b.21064

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A systematic analysis of bone marrow cells by flow cytometry defines a specific phenotypic profile beyond GPI deficiency in paroxysmal nocturnal hemoglobinuria.PMID 23281097Read ↗

Application of flow cytometry to the diagnosis of paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Detailed immunophenotypic characterization of different major and minor subsets of peripheral blood cells in patients with paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

[Paroxysmal nocturnal hemoglobinuria].Semantic proximity Read ↗

Quantitative analysis of the expression of glycosylphosphatidylinositol‐anchored proteins during the maturation of different hematopoietic cell compartments of normal bone marrowSemantic proximity Read ↗

ICCS/ESCCA consensus guidelines to detect GPI-deficient cells in paroxysmal nocturnal hemoglobinuria (PNH) and related disorders part 1 - clinical utility.Semantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria (PNH): higher sensitivity and validity in diagnosis and serial monitoring by flow cytometric analysis of reticulocytesSemantic proximity Read ↗

Recent advances in paroxysmal nocturnal hemoglobinuria. From the biology to the clinic.Semantic proximity Read ↗

Recent advances in the diagnosis, monitoring, and management of patients with paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Recent insights into the pathophysiology of paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

Recent advances in the pathogenesis and treatment of paroxysmal nocturnal hemoglobinuriaSemantic proximity Read ↗

Paroxysmal nocturnal hemoglobinuria: insights from recent advances in molecular biology.Semantic proximity Read ↗

New insights into paroxysmal nocturnal hemoglobinuria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.