Article
VEGF polymorphisms are not associated with an increased risk of developing renal cell carcinoma in Spanish population.
Human immunology - 1 Jan 2013
Sáenz-López Pablo, Vazquez Fernando, Cozar Jose Manuel, Carretero Rafael, Garrido Federico, Ruiz-Cabello Francisco
Abstract excerpt
PURPOSE: Vascular endothelial growth factor (VEGF) plays a central role in promoting angiogenesis and is over-expressed in renal cell cancer (RCC). Published data on the association between polymorphisms of vascular endothelial growth factor (e.g., -2578C/A [rs699947], -460T/C [rs833061], +405C/G [rs2010963], and +936C/T [rs3025039]) and the risk of renal cell carcinoma are ambiguous and controversial. The aim of...
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