Article
Structure of the DNA binding wing of the gene-V encoded single- stranded DNA binding protein of the filamentous bacteriophage M13.
FEBS letters - 12 Feb 1990
van Duynhoven J P, Folkers P J, Stassen A P, Harmsen B J, Konings R N, Hilbers C W
Abstract excerpt
The structure in solution of a beta-loop in mutant Y41H of the single-stranded DNA binding protein encoded by gene-V of the filamentous phage M13 has been elucidated using 2-dimensional 1H-nuclear magnetic resonance techniques. Furthermore, these studies enabled us to demonstrate that an identical structural element is present in wild-type gene-V-protein and that this element intimately is involved in the binding...
Topics
- Amino Acid Sequence
- Bacteriophages
- DNA, Single-Stranded
- DNA-Binding Proteins
- Genes, Viral
- Magnetic Resonance Spectroscopy
- Molecular Sequence Data
- Molecular Structure
- Mutation
- Protein Conformation