Article
A genome-wide association study of serum levels of prostate-specific antigen in the Japanese population.
Journal of medical genetics - 1 Aug 2014
Terao Chikashi, Terada Naoki, Matsuo Keitaro, Kawaguchi Takahisa, Yoshimura Koji, Hayashi Norio, Shimizu Masakazu, Soga Norihito, Takahashi Meiko, Kotoura Yoshihiko, Yamada Ryo, Ogawa Osamu, Matsuda Fumihiko
Abstract excerpt
BACKGROUND: Prostate-specific antigen (PSA) is a useful marker for prostate cancer (PCa) and is widely used for screening of PCa. Previous studies have shown that genetic components influence the levels of PSA, and some of these genetic components would lead to better diagnostic sensitivity and specificity to PCa. However, genetic studies for PSA from Asian countries are limited. Our aim was to identify genetic...
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