The use of primary human fibroblasts for monitoring mitochondrial phenotypes in the field of Parkinson's disease.

Abstract excerpt

Parkinson's disease (PD) is the second most common movement disorder and affects 1% of people over the age of 60 (1). Because ageing is the most important risk factor, cases of PD will increase during the next decades (2). Next to pathological protein folding and impaired protein degradation pathways, alterations of mitochondrial function and morphology were pointed out as further hallmark of neurodegeneration in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biopsy
• Share to Fibroblasts
• Share to Flow Cytometry