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Article

GNAS A-1121G variant is associated with improved diastolic dysfunction in response to exercise training in heart failure patients.

International journal of sports medicine - 1 Mar 2013

Alves A J, Goldhammer E, Ribeiro F, Eynon N, Ben-Zaken Cohen S, Duarte J A, Viana J L, Sagiv M, Oliveira J

Abstract excerpt

β1-adrenergic receptors (ADRB1) and Gαs proteins (GNAS) play important roles in the regulation of cardiac function. The present study sought to investigate whether ADRB1 Arg389Gly (rs1801253), GNAS -1211 G/A (rs6123837) and GNAS 2291 C/T (rs6026584) variants are associated with left ventricular f...

Read the complete abstract on PubMed

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Topics

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Share to Chromogranins
Share to Exercise Test
Share to Exercise Therapy
Share to Exercise Tolerance
Share to GTP-Binding Protein alpha Subunits, Gs
Share to Receptors, Adrenergic, beta-1
Share to Ultrasonography
Share to Ventricular Function, Left

Source

Identifiers

PMID: 23065660
DOI: 10.1055/s-0032-1316365

Genes

GNAS
ADRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23065660-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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