Article
Fragile X mental retardation 1 (FMR1) intron 1 methylation in blood predicts verbal cognitive impairment in female carriers of expanded FMR1 alleles: evidence from a pilot study.
Clinical chemistry - 1 Mar 2012
Godler David E, Slater Howard R, Bui Quang M, Storey Elsdon, Ono Michele Y, Gehling Freya, Inaba Yoshimi, Francis David, Hopper John L, Kinsella Glynda, Amor David J, Hagerman Randi J, Loesch Danuta Z
Abstract excerpt
BACKGROUND: Cognitive status in females with mutations in the FMR1 (fragile X mental retardation 1) gene is highly variable. A biomarker would be of value for predicting which individuals were liable to develop cognitive impairment and could benefit from early intervention. A detailed analysis of...
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