Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic lymphocytic leukemia with del13q14 as the sole abnormality: dynamic prognostic estimate by interphase-FISH.

Hematological oncology - 1 Sept 2013

Orlandi Ester M, Bernasconi Paolo, Pascutto Cristiana, Giardini Ilaria, Cavigliano Paola M, Boni Marina, Zibellini Silvia, Cazzola Mario

Abstract excerpt

This study analyzed 140 patients with isolated del13q14 on interphase FISH (I-FISH), to identify subsets with a different progression risk and to assess the acquisition of additional chromosomal abnormalities (clonal evolution) in treatment-naïve del13q14 patients. A monoallelic deletion (del13qx1) was detected in 123 cases (88%), a biallelic deletion (del13qx2) in eight and a mosaic of monoallelic and biallelic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-ribosyl Cyclase 1
Share to Chromosomes, Human, Pair 13

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Clone Cells

Share to Genes, Retinoblastoma

Share to Interphase

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Retinoblastoma Protein

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 23060227
DOI: 10.1002/hon.2032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic lymphocytic leukemia with del13q14 as the sole abnormality: dynamic prognostic estimate by interphase-FISH.PMID 23060227Read ↗

13q14 Deletion size and number of deleted cells both influence prognosis in chronic lymphocytic leukemiaSemantic proximity Read ↗

A comprehensive evaluation of the prognostic significance of 13q deletions in patients with B‐chronic lymphocytic leukaemiaSemantic proximity Read ↗

A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemiaSemantic proximity Read ↗

Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia.Semantic proximity Read ↗

The Heterogeneity of 13q Deletions in Chronic Lymphocytic Leukemia: Diagnostic Challenges and Clinical ImplicationsSemantic proximity Read ↗

Biallelic deletion 13q14.3 in patients with chronic lymphocytic leukemia: cytogenetic, FISH and clinical studiesSemantic proximity Read ↗

Molecular characterization of chronic lymphocytic leukemia patients with a high number of losses in 13q14.Semantic proximity Read ↗

High-risk clonal evolution in chronic B-lymphocytic leukemia: single-center interphase fluorescence in situ hybridization study and review of the literature.Semantic proximity Read ↗

Biallelic losses of 13q do not confer a poorer outcome in chronic lymphocytic leukaemia: analysis of 627 patients with isolated 13q deletion.Semantic proximity Read ↗

Molecular pathogenesis of B-cell chronic lymphocytic leukemia: analysis of 13q14 chromosomal deletions.Semantic proximity Read ↗

Biological and clinical characterization of recurrent 14q deletions in CLL and other mature B-cell neoplasms.Semantic proximity Read ↗

13q deletion anatomy and disease progression in patients with chronic lymphocytic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.