Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biological and clinical characterization of recurrent 14q deletions in CLL and other mature B-cell neoplasms.

British journal of haematology - 1 Oct 2010

Reindl Lena, Bacher Ulrike, Dicker Frank, Alpermann Tamara, Kern Wolfgang, Schnittger Susanne, Haferlach Torsten, Haferlach Claudia

Abstract excerpt

14q-deletions have been repeatedly described in mature B-cell neoplasms, but not yet characterized in a larger cohort. Based on chromosome banding analysis, the present study identified 47 del(14q) cases in 3054 mature B-cell neoplasms (1·5%) (chronic lymphocytic leukaemia [CLL]: 1·9%; CLL/prolymphocytic leukaemia [PL]: 9·0%; others: 0·2%). Interphase fluorescence in situ hybridization was performed with probes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 14

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to In Situ Hybridization, Fluorescence

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Survival Analysis

Source

Identifiers

PMID: 20649559
DOI: 10.1111/j.1365-2141.2010.08299.x

Genes

IGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biological and clinical characterization of recurrent 14q deletions in CLL and other mature B-cell neoplasms.PMID 20649559Read ↗

Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosisSemantic proximity Read ↗

t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)Semantic proximity Read ↗

14q deletions are associated with trisomy 12, NOTCH1 mutations and unmutated IGHV genes in chronic lymphocytic leukemia and small lymphocytic lymphoma.Semantic proximity Read ↗

The prognostic significance of various 13q14 deletions in chronic lymphocytic leukemia.Semantic proximity Read ↗

An increased frequency of 13q deletions detected by fluorescence <i>in situ</i> hybridization and its impact on survival in children and adolescents with Burkitt lymphoma: results from the Children’s Oncology Group study CCG‐5961Semantic proximity Read ↗

Molecular pathogenesis of B-cell chronic lymphocytic leukemia: analysis of 13q14 chromosomal deletions.Semantic proximity Read ↗

A high number of losses in 13q14 chromosome band is associated with a worse outcome and biological differences in patients with B-cell chronic lymphoid leukemiaSemantic proximity Read ↗

The Heterogeneity of 13q Deletions in Chronic Lymphocytic Leukemia: Diagnostic Challenges and Clinical ImplicationsSemantic proximity Read ↗

Chronic lymphocytic leukemia with del13q14 as the sole abnormality: dynamic prognostic estimate by interphase-FISH.Semantic proximity Read ↗

Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14.Semantic proximity Read ↗

Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomasSemantic proximity Read ↗

13q14 Deletion and Its Effect on Prognosis of Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.