Article
Impact of uremia on human adipose tissue phenotype.
The Journal of surgical research - 1 Jan 2013
Ho Karen J, Xue Hui, Mauro Christine R, Nguyen Binh, Yu Peng, Tao Ming, Seidman Michael A, Brunelli Steven M, Ozaki Charles Keith
Abstract excerpt
BACKGROUND: Recognition of adipose-related signaling in surgery is increasing, although direct interrogation of human adipose has been sparse. Few scenarios rival uremia for health impact. We hypothesized that adipose from uremic patients holds a relatively higher adipose-derived hormone and proinflammatory adipokine signature; we simultaneously evaluated the impact of clinical parameters on adipose phenotype....
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