Article
The emerging pleiotrophic role of adipokines in the uremic phenotype.
Current opinion in nephrology and hypertension - 1 Jan 2010
Carrero Juan Jesús, Cordeiro Antonio Carlos, Lindholm Bengt, Stenvinkel Peter
Abstract excerpt
PURPOSE OF REVIEW: The obesity epidemic is undoubtedly increasing the total end-stage renal disease population, which has a larger proportion of obese individuals on reaching the dialysis stage. This review discusses recent advances in the pathophysiology of adipose tissue and adipokines that may contribute to increased risk of progression towards end-stage renal disease and cardiovascular damage. RECENT...
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