Article
Inflammatory "adiposopathy" in major amputation patients.
Annals of vascular surgery - 1 Apr 2013
Mauro Christine R, Nguyen Binh T, Yu Peng, Tao Ming, Gao Ian, Seidman Michael A, Nguyen Louis L, Ozaki C Keith
Abstract excerpt
BACKGROUND: Much has been made of obesity's health impact, largely founded on data regarding patient weight and circulating adipose-derived mediator levels. Paradoxically, a "healthy obese" state exists, but substantial knowledge gaps also exist regarding human adipose-phenotype determinants. Surgical major amputation (AMP) patients are the "sickest-of-the-sick." Conversely, elective knee replacement (TKR) is...
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