Article
Genetics of polycystic ovary syndrome.
Frontiers of hormone research - 1 Jan 2013
Barber Thomas M, Franks Stephen
Abstract excerpt
Polycystic ovary syndrome (PCOS) is an oligogenic condition, with a heritability of ∼70%. PCOS is also associated with obesity, which itself is heavily influenced by genetic variants. PCOS is inherently difficult to study genetically, and most of the current literature (>70 studies based on the candidate gene approach) is inconclusive, with many studies being underpowered resulting in inconsistencies,...
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