Article
A Tail-like Assembly at the Portal Vertex in Intact Herpes Simplex Type-1 Virions
4 Oct 2012
Abstract excerpt
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA viruses. However, such machinery is well characterized in tailed bacteriophage, which share a common evolutionary origin with herpesvirus. In tailed bacteriophage, the...