Article
Role of the Herpes Simplex Virus CVSC Proteins at the Capsid Portal Vertex
22 Sept 2020
Abstract excerpt
Herpes simplex virus 1 (HSV-1) is the causative agent of several pathologies ranging in severity from the common cold sore to life-threatening encephalitic infection. A critical step during productive HSV-1 infection is the cleavage and packaging of replicated, concatemeric viral DNA into preformed capsids. A key knowledge gap is how the capsid engages the replicated viral genome and the subsequent packaging of a...
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