Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

OGG1 gene sequence variation in head and neck cancer patients in Pakistan.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Mahjabeen Ishrat, Baig Ruqia Mehmood, Masood Nosheen, Sabir Maimoona, Malik Faraz Arshad, Kayani Mahmood Akhtar

Abstract excerpt

In Pakistani culture tobacco use is very high and a well known risk factor for developing head and neck cancer (HNC), tobacco smoke containing high quantities of chemical carcinogens such as aromatic amines and reactive oxygen species. OGG1 is the primary enzyme in the base excision repair (BER) pathway, responsible for the excision of 7, 8-dihydro-8-oxoguanine, a mutagenic base byproduct that occurs as a result...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Glycosylases
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frameshift Mutation

Share to Germ-Line Mutation

Share to Head and Neck Neoplasms

Share to Pakistan

Share to Smoking

Share to Tobacco Use Disorder

Source

Identifiers

PMID: 22320992

Genes

OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

OGG1 gene sequence variation in head and neck cancer patients in Pakistan.PMID 22320992Read ↗

Novel mutations of OGG1 base excision repair pathway gene in laryngeal cancer patients.Semantic proximity Read ↗

Genetic variations in XRCC1 gene in sporadic head and neck cancer (HNC) patients.Semantic proximity Read ↗

Interaction between human oxoguanine glycosylase 1 gene polymorphisms and smoking status on nasopharyngeal carcinoma risk.Semantic proximity Read ↗

Is Human Oxoguanine Glycosylase 1 Genetic Variant Successful Even on Oral Squamous Cell Carcinoma?Semantic proximity Read ↗

Protective association exhibited by the single nucleotide polymorphism (SNP) rs1052133 in the gene human 8-oxoguanine DNA glycosylase (hOGG1) with the risk of squamous cell carcinomas of the head & neck (SCCHN) among north Indians.Semantic proximity Read ↗

Haplotype CGC from XPD, hOGG1 and ITGA2 polymorphisms increases the risk of nasopharyngeal carcinoma in Malaysia.Semantic proximity Read ↗

Characterization of genetic polymorphisms in oral cancer-related genes pertaining to oxidative stress, carcinogen detoxifying, and DNA repair: A case-control study.Semantic proximity Read ↗

Genetic Investigation of Polymorphic OGG1 and MUTYH Genes Towards Increased Susceptibility in Lung Adenocarcinoma and its Impact on Overall Survival of Lung Cancer Patients Treated with Platinum Based Chemotherapy.Semantic proximity Read ↗

Involvement of single-nucleotide polymorphisms in predisposition to head and neck cancer in Saudi Arabia.Semantic proximity Read ↗

Rb1/105 gene alterations and head and neck carcinogenesis.Semantic proximity Read ↗

Genetic variations and head and neck cancer risks.Semantic proximity Read ↗

Association of GSTM1 and GSTT1 gene deletions with risk of head and neck cancer in Pakistan: a case control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.