Article
3'-UTR OLR1/LOX-1 gene polymorphism and endothelial dysfunction: molecular and vascular data in never-treated hypertensive patients.
Internal and emergency medicine - 1 Apr 2014
Sciacqua Angela, Presta Ivan, Perticone Maria, Tassone Eliezer J, Andreozzi Francesco, Quitadamo Maria Chiara, Sangiuolo Federica Carla, Sesti Giorgio, Perticone Francesco
Abstract excerpt
Endothelial dysfunction represents an independent predictor for clinical events. Genetic background may promote deleterious alterations of endothelial physiology. The aim of the study was to investigate the relationship between the rs1050283 polymorphism in the 3'-UTR of OLR1/LOX-1 gene and endothelial dysfunction in 178 never-treated hypertensive patients and 36 healthy subjects. The rs1050283 C/T single...
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