Article
Effects of the APOE ε2 allele on mortality and cognitive function in the oldest old.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Apr 2013
Lindahl-Jacobsen Rune, Tan Qihua, Mengel-From Jonas, Christensen Kaare, Nebel Almut, Christiansen Lene
Abstract excerpt
Some studies indicate that the APOE ε2 allele may have a protective effect on mortality and mental health among the elderly adults. We investigated the effect of the APOE ε2 allele on cognitive function and mortality in 1651 members of the virtually extinct Danish 1905 birth cohort. We found no protective effect of the APOE ε2 allele on mortality compared with the APOE ε3 allele. The point estimates indicated an...
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