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Article

Apolipoprotein E ε4 and cognitive function after surgery in middle-aged and elderly Danish twins.

European journal of anaesthesiology - 1 Nov 2020

Dokkedal Unni, Wod Mette, Thinggaard Mikael, Hansen Tom G, Rasmussen Lars S, Christensen Kaare, Mengel-From Jonas

Abstract excerpt

BACKGROUND: Transient cognitive impairment is common in adult patients of all ages following anaesthesia and surgery. Apolipoprotein E (APOE) ε4 carriers may have a larger deterioration in short-term cognitive function after major surgery compared with APOE ε4 noncarriers. OBJECTIVES: The aim was to examine the effect of APOE ε4 on the association between exposure to surgery and anaesthesia, and subsequent...

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Identifiers

PMID: 32618758
DOI: 10.1097/EJA.0000000000001250
PMCID: PMC7680924

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