Association of the polymorphism of DR4 with the risk and severity of lumbar disc degeneration in the Chinese Han population.

doi:10.3109/00365513.2012.713176

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Article

Association of the polymorphism of DR4 with the risk and severity of lumbar disc degeneration in the Chinese Han population.

Scandinavian journal of clinical and laboratory investigation - 1 Nov 2012

Tan Haitao, Zhao Jinmin, Jiang Jianzhong, Ren Yingang

Abstract excerpt

OBJECTIVE: Death receptor 4 (DR4), an apoptosis-associated gene, plays an important role in the pathophysiology of lumbar disc degeneration (LDD). The present study aimed to determine whether the C626G polymorphism (rs4871857) of the DR4 gene is associated with the risk and severity of LDD in the Chinese Han population. METHODS: A total of 296 patients with LDD and 208 healthy controls were enrolled in this...

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PMID: 23050498
DOI: 10.3109/00365513.2012.713176

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