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Article

Single-nucleotide gene polymorphisms involving cell death pathways: a study of Chinese patients with lumbar disc herniation.

Connective tissue research - 1 Jan 2013

Sun Zhengming, Ling Ming, Chang Yanhai, Huo Yuping, Yang Guang, Ji Yuqiang, Li Yaping

Abstract excerpt

OBJECTIVE: To evaluate the effect of polymorphisms of death pathway genes FAS and FASL on the risk of developing lumbar disc herniation (LDH) in a Northern Chinese population. BACKGROUND DATA: The FAS receptor-ligand system plays a key role to regulate apoptosis of cell. There is evidence that the apoptosis-mediated FAS receptor-ligand system is involved in the pathogenesis of disc degeneration. Some research...

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Source

Identifiers

PMID: 23205884
DOI: 10.3109/03008207.2012.734878

Genes

FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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