Article
Association of FAS and FAS ligand polymorphisms with the susceptibility and severity of lumbar disc degeneration in Chinese Han population.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Sept 2011
Zhu Guang-Bin, Jiang Xiao-Rui, Xia Chen-Lai, Sun Yong-Jian, Zeng Qing-Si, Wu Xiao-Mei, Li Xin-Chun
Abstract excerpt
CONTEXT: Apoptosis is involved in the mechanism of lumbar disc degeneration (LDD). OBJECTIVE: We aim to determine whether the polymorphisms of FAS and FASL are associated with the presence and severity of LDD. METHODS: A total of 348 patients with LDD and 215 healthy controls were genotyped. RESU...
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