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Article

A genome-wide scan maps a novel high myopia locus to 5p15.

Investigative ophthalmology & visual science - 1 Sept 2008

Lam Ching Yan, Tam Pancy O S, Fan Dorothy S P, Fan Bao Jian, Wang Dan Yi, Lee Coral W S, Pang Chi Pui, Lam Dennis S C

Abstract excerpt

PURPOSE: This study was conducted to investigate the genetic component of three Chinese pedigrees originating from Hong Kong with autosomal dominant high myopia. METHODS: A whole-genome scan was performed by using microsatellite markers spanning the whole genome with an average spacing of 10 cM. Regions containing markers that yielded LOD scores >1.0 were further analyzed by fine mapping with additional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18421076
DOI: 10.1167/iovs.07-1126

Genes

CCT5
CTNND2
IRX1
IRX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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