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Telomeric repeat-containing RNA and telomerase in human fetal oocytes

9 Oct 2012

Abstract excerpt

STUDY QUESTION: What is the distribution of telomeric repeat-containing RNA (TERRA) and of telomerase in human fetal oocytes? SUMMARY ANSWER: TERRA forms discrete foci at telomeres of human fetal oocytes and it co-localizes with both the shelterin component telomeric repeat-binding factor 2 (TRF2) and the catalytic subunit of human telomerase at the telomeres of meiotic chromosomes. WHAT IS KNOWN ALREADY: TERRA...

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Share to Chromosomal and Genetic Variations
Share to Prenatal Screening and Diagnostics
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PMID: 23049077
DOI: 10.1093/humrep/des363

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